Preheat the oven to 350°F (175°C). Grease and flour two 9-inch round cake pans.
In a large mixing bowl, combine the flour, sugar, baking soda, salt, and cocoa powder.
Add the vegetable oil, buttermilk, eggs, food coloring, vinegar, and vanilla extract. Mix until well combined.
Divide the batter evenly between the prepared pans. Smooth the tops with a spatula.
Bake for 25-30 minutes, or until a toothpick inserted into the center of the cakes comes out clean.
Allow the cakes to cool in the pans for 10 minutes, then transfer them to a wire rack to cool completely.
Once the cakes are cooled, frost with cream cheese frosting. Serve and enjoy!